Third Trimester Estrogens and Maternal Breast Cancer: Prospective Evidence
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چکیده
منابع مشابه
Estrogens, BRCA1, and breast cancer.
Findings obtained in in vitro assays and animal studies indicate that estrogens might influence the activity of the tumor suppressor gene BRCA1, and BRCA1 in turn may suppress the activity of the estrogen receptor. This review will discuss the possibility that interactions between estrogens and BRCA1 partly explain why elevated circulating estrogen levels appear to increase breast cancer risk a...
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Breast cancer prevention and control may benefit by elucidation of natural protective mechanisms. Pregnancy is an excellent model for studying protective mechanisms under conditions of promotion, when women are exposed to a variety of growth factors and hormones. The purpose of our research was to test the hypothesis that maternal serum levels of steroid hormones can explain novel protective as...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2017
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2016-3476